Brain Is a Co-Conspirator in a Vicious Stress Loop

If after a few months’ exposure to our David Lynch economy, in which housing markets spontaneously combust, coworkers mysteriously disappear and the stifled moans of dying 401(k) plans can be heard through the floorboards, you have the awful sensation that your body’s stress response has taken on a self-replicating and ultimately self-defeating life of its own, congratulations. You are very perceptive. It has.

As though it weren’t bad enough that chronic stress has been shown to raise blood pressure, stiffen arteries, suppress the immune system, heighten the risk of diabetes, depression and Alzheimer’s disease and make one a very undesirable dinner companion, now researchers have discovered that the sensation of being highly stressed can rewire the brain in ways that promote its sinister persistence.

Reporting earlier this summer in the journal Science, Nuno Sousa of the Life and Health Sciences Research Institute at the University of Minho in Portugal and his colleagues described experiments in which chronically stressed rats lost their elastic rat cunning and instead fell back on familiar routines and rote responses, like compulsively pressing a bar for food pellets they had no intention of eating.

Moreover, the rats’ behavioral perturbations were reflected by a pair of complementary changes in their underlying neural circuitry. On the one hand, regions of the brain associated with executive decision-making and goal-directed behaviors had shriveled, while, conversely, brain sectors linked to habit formation had bloomed.

In other words, the rodents were now cognitively predisposed to keep doing the same things over and over, to run laps in the same dead-ended rat race rather than seek a pipeline to greener sewers. “Behaviors become habitual faster in stressed animals than in the controls, and worse, the stressed animals can’t shift back to goal-directed behaviors when that would be the better approach,” Dr. Sousa said. “I call this a vicious circle.”

Robert Sapolsky, a neurobiologist who studies stress at Stanford University School of Medicine, said, “This is a great model for understanding why we end up in a rut, and then dig ourselves deeper and deeper into that rut.”

The truth is, Dr. Sapolsky said, “we’re lousy at recognizing when our normal coping mechanisms aren’t working. Our response is usually to do it five times more, instead of thinking, maybe it’s time to try something new.”

And though perseverance can be an admirable trait and is essential for all success in life, when taken too far it becomes perseveration — uncontrollable repetition — or simple perversity. “If I were to try to break into the world of modern dance, after the first few rejections the logical response might be, practice even more,” said Dr. Sapolsky, the author of “Why Zebras Don’t Get Ulcers,” among other books. “But after the 12,000th rejection, maybe I should realize this isn’t a viable career option.”

Happily, the stress-induced changes in behavior and brain appear to be reversible. To rattle the rats to the point where their stress response remained demonstrably hyperactive, the researchers exposed the animals to four weeks of varying stressors: moderate electric shocks, being encaged with dominant rats, prolonged dunks in water. Those chronically stressed animals were then compared with nonstressed peers. The stressed rats had no trouble learning a task like pressing a bar to get a food pellet or a squirt of sugar water, but they had difficulty deciding when to stop pressing the bar, as normal rats easily did.

But with only four weeks’ vacation in a supportive setting free of bullies and Tasers, the formerly stressed rats looked just like the controls, able to innovate, discriminate and lay off the bar. Atrophied synaptic connections in the decisive regions of the prefrontal cortex resprouted, while the overgrown dendritic vines of the habit-prone sensorimotor striatum retreated.

According to Bruce S. McEwen, head of the neuroendocrinology laboratory at Rockefeller University, the new findings offer a particularly elegant demonstration of a principle that researchers have just begun to grasp. “The brain is a very resilient and plastic organ,” he said. “Dendrites and synapses retract and reform, and reversible remodeling can occur throughout life.”

Stress may be most readily associated with the attosecond pace of postindustrial society, but the body’s stress response is one of our oldest possessions. Its basic architecture, its linked network of neural and endocrine organs that spit out stimulatory and inhibitory hormones and other factors as needed, looks pretty much the same in a goldfish or a red-spotted newt as it does in us.

The stress response is essential for maneuvering through a dynamic world — for dodging a predator or chasing down prey, swinging through the trees or fighting off disease — and it is itself dynamic. As we go about our days, Dr. McEwen said, the biochemical mediators of the stress response rise and fall, flutter and flare. “Cortisol and adrenaline go up and down,” he said. “Our inflammatory cytokines go up and down.”

The target organs of stress hormones likewise dance to the beat: blood pressure climbs and drops, the heart races and slows, the intestines constrict and relax. This system of so-called allostasis, of maintaining control through constant change, stands in contrast to the mechanisms of homeostasis that keep the pH level and oxygen concentration in the blood within a narrow and invariant range.

Unfortunately, the dynamism of our stress response makes it vulnerable to disruption, especially when the system is treated too roughly and not according to instructions. In most animals, a serious threat provokes a serious activation of the stimulatory, sympathetic, “fight or flight” side of the stress response. But when the danger has passed, the calming parasympathetic circuitry tamps everything back down to baseline flickering.

In humans, though, the brain can think too much, extracting phantom threats from every staff meeting or high school dance, and over time the constant hyperactivation of the stress response can unbalance the entire feedback loop. Reactions that are desirable in limited, targeted quantities become hazardous in promiscuous excess. You need a spike in blood pressure if you’re going to run, to speedily deliver oxygen to your muscles. But chronically elevated blood pressure is a source of multiple medical miseries.

Why should the stressed brain be prone to habit formation? Perhaps to help shunt as many behaviors as possible over to automatic pilot, the better to focus on the crisis at hand. Yet habits can become ruts, and as the novelist Ellen Glasgow observed, “The only difference between a rut and a grave are the dimensions.”

It’s still August. Time to relax, rewind and remodel the brain.

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Source:

http://www.nytimes.com/2009/08/18/science/18angier.html?_r=1

Tags:

Bruce S. McEwen, neuroendocrinology laboratory, Rockefeller University, Dendrites, synapses, Ellen Glasgow, neural, endocrine organs, stimulatory, inhibitory hormone, chronic stress, brain research,

Posted via email from Global Business News

Gold-plated Roman horse head found

Scientists say a Roman horse head made from bronze and plated in gold has been discovered at an archaeological site in Germany.

Hesse state archaeologist Egon Schallmeyer says the head is part of a horse and rider statue and "qualitatively one of the best (pieces) created at that time."

The ornamented, well preserved head was found earlier this month at the Waldgirmes excavation site in central Germany and displayed Thursday at the German Archaeological Institute in Frankfurt.

Archaeologists have been digging since 1993 at the site, a Roman city during the reign of Emperor Caesar Augustus from 23 B.C. to 14 A.D.

Other parts of the life-sized statue were found earlier and include a foot and a decorated chest strap.

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Source:

http://www.msnbc.msn.com/id/32581452/ns/technology_and_science-science/

Tags:

Frankfurt, Hesse state, archaeology, Egon Schallmeyer, Waldgirmes excavation site, central Germany, German Archaeological Institute, Archaeologists, Roman city, Emperor Caesar Augustus,

Posted via email from Global Business News

High Frequency Trading: The Rise of the Machines

As a professional trader, you are confronted daily with all kinds of dynamics and situations that require a flexible and adaptive mind. You are faced with multiple variables constantly interacting with each other and your task is to process ever-changing information quickly and profitably. Valuations arbitrage, reflexive supply-and-demand dynamics, and structural changes are recurrent landmines in the typical day of traders and money managers.

We accept this “dangerous” line of work for only two reasons: monetary compensation and pride in being part of capital markets, that transmission mechanism without which innovation and creativity would be prisoners of their own ethereal state.

As a society, we are ready to strike compromises in return for a system that will allow the ethereal state of our creativity to turn into reality. We allow market insiders like market makers, broker-dealers, and others to have small advantages over us mortal investors in order to have them create the positive externalities that help us build a more sophisticated economic system. We give market makers and specialists a privileged look at the order flow (the supply and demand of stocks) in exchange for their commitment to maintaining orderly markets whenever an imbalance occurs.

We give systemic firms like JP Morgan and Goldman Sachs privileged access to liquidity via the Federal Reserve so that the banking system and capital markets can continue to serve us in our quest to invent, produce, and distribute new products. But sometimes things turn out more like a bad inland casino rather than a better market… We may still be reeling from the systemic economic collapse of last year, but new structural changes with potential negative externalities are already at our door.

For months I have witnessed strange dynamics in the way markets behaved: liquidity issues, intra-day volatility, and a constant disconnection between technical, sentiment and fundamental inputs. Markets often go through periods of irrationality, but this time it felt different.

As a professional trader and an educator on markets, my sensitivity level is higher than normal and I immediately began conducting research to make sense of my discomfort. This process pointed consistently to one element: high frequency trading or as I like to call it “the rise of the machines.”

What is High Frequency Trading?

High frequency trading (HFT) was, until recently, a topic confined to Wall Street insiders. Only in the last few weeks has it become a mainstream subject of debate via articles on theNew York Times, the Washington Post, and interviews on CNBC (yes even CNBC’s clueless anchors can now spell HFT).

The reason for this foray into the mainstream media is the potential negative ramifications HFT can have for all of us: investors, entrepreneurs, and just plain hopeful citizens.

But first, let’s define HFT as it is a very technical classification that, nonetheless, encompasses many different things. Generally speaking, HFT is high velocity trading based on mathematical algorithms that create huge daily volume on different electronic exchanges and platforms. It is machine against machine—endless trading in order to capture fractions of pennies in profits. But, so far so good: the machines provide liquidity to all of us. The owners of the machines (financial institutions) make an all-American profit and the liquidity aggregators (electronic exchanges) provide competition to other exchanges in the most capitalistic way.

But what happens if we scratch the surface? Like Michel de Montaigne, the famed Renaissance scholar, once said: “There is no man so good, who, were he to submit all his thoughts and actions to the law would not deserve hanging ten times over.”

High frequency algorithmic trading is ridden with issues:

Volume. Machine-driven trading is over 60% of trading volume on a daily basis and in some confined cases it can be as high as 90%.

Adaptability. Machines are unthinking units that do not adapt to human reactions. HFT algorithms are based on correlations and historical relationships, which are great guidelines for trading and investing but by no means they can be used blindly (see: 1987 portfolio insurance, long-term capital management 1998, credit default swaps 2008, mortgage-backed securities 2008…the list of quant-related disasters is a sad one).

Exclusivity. HFT can only work by using incredibly fast and powerful computers that also must be placed in the exchanges as proximity helps the speed. Few people can afford the computers and/or the co-location fees charged by the electronic exchanges.

Flash quotes. Some brokers have access to quotes of orders before anyone else. By exploiting the speed of their machines, they can either arbitrage price differentials or potentially front-run clients. Another abuse of flash quotes (called flash because they last one–to-three milliseconds) is that they can be used as teaser quotes to gauge supply and demand without the risk of being hit due to their quickness.

Rebates. Many high frequency traders trade not for profit but for rebates paid by the electronic platforms to attract liquidity. This escamotage incentivizes useless and toxic volume.

While these are only the most immediate concerns about HFT, they have a potentially disproportionate influence on the cost of running our capital markets. The HFT lobby pushes the argument that they create positive externalities by exploiting improving technology—but there is a difference between volume and liquidity.

If over 60% of trading is toxic, it will go away in a nanosecond and most likely it will dissipate right when investors and money managers need it the most. This could cause a huge liquidity vacuum and a 1987-type of event. Liquidity is created by market players with a stake in the game, not by casino-like machines. Flash quotes and “predatory algorithms” also raise the cost of execution for the necessarily slower institutions like pension funds and mutual funds. Additionally, the surreal tempo of machine trading makes trading for all more expensive as we now have to prepare for the irrational moves and volatility of markets when executing our trades.

I love this business and I love technology, but checks and balances are needed to preserve our capital markets. Little adjustments can be made to reduce systemic risk, like re-instating circuit breakers that cut off program trading when price changes accelerate beyond certain parameters, like investigation or stopping flash quotes that drive front running, like making good on teaser quotes for longer than just three milliseconds, and so on. In the end, we need to understand that capital markets are here not to destabilize our economy, but to serve us as a society and help us make better lives.

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Russian, Ukrainian Tug of War Over History

Russian historians widely recognize June 27, 1709 as the date their country became a great power. Russia that day defeated an invading Swedish army at Poltava in Ukraine, where Ukrainian forces allied with Sweden were also vanquished. The Battle of Poltava is not just history, but another source of ongoing friction between Moscow and Kyiv.

Poltava is recognized as the pivotal battle in the Great Northern War, a 21-year struggle, in which Russia replaced Sweden as the great power of Northern Europe in the early 18th century. Poltava also ended Ukrainian aspirations for independence from Russia.

"Traitor Mazepa"

The leader of the Ukrainian forces, Ivan Mazepa, remains a source of controversy between Moscow and Kyiv. Mazepa was Ukraine's so-called Hetman, or leader of its Cossack military forces.

In Russia he is considered a traitor who betrayed an oath of allegiance to Czar Peter the Great, the victorious commander at Poltava. The term "traitor Mazepa" remains a common Russian term. He was cast as a villain in works by Russian poet Alexander Pushkin and composer Peter Tchaikovsky, and also excommunicated by the Russian Orthodox Church. That decision is still in effect, despite recent high level requests from Ukrainian political and church leaders to rescind the move.

But Ukrainians say the Hetman was forced to side with Sweden, because Russian ruler Peter the Great failed to honor a 1654 treaty to protect their land against Polish attacks. But until the collapse of the Soviet Union, Russia considered the same treaty to have been an agreement by Ukraine for an everlasting union with its northern neighbor.

Ukrainians also consider Mazepa to have been a great reformer, who built schools and publishing houses, expanded higher learning, and supported the arts, including a distinctly Ukrainian style of church architecture that dominates the modern skyline of Kyiv.

Mazepa's portrait appears on Ukraine's 10-hryvna currency note, and the country will soon unveil a monument to him in Poltava. Last month, the Russian Foreign Ministry issued a statement condemning the statue as divisive. At a recent Poltava conference in Moscow, Vladimir Artamonov of the Russian Academy of Sciences told fellow historians the battle liberated Ukraine from Swedish invaders.

Artamanov says Poltava was not a tragedy for Ukraine, but rather a tragedy for Mazepa and his followers who sought to subordinate "Little Russia" to Poland. Russians often use the term "Little Russia" as a synonym for Ukraine. Many Ukrainians resent it as demeaning.

Genocide issues

Speaking at the same Moscow conference, Ukrainian historian Serhiy Poltavets said it is important to consider why Mazepa allied himself with Sweden. Poltavets says documentary evidence indicates that Mazepa's goal was to create an independent Ukraine; that his goal contradicted the political and geopolitical aims of the Russian state is something, which cannot be denied.

Moscow and Kyiv are also at odds over historic assessments of an artificial famine during the period of Soviet land collectivization in the early 1930's that claimed the lives of millions, particularly in Ukraine, Russia and Kazakhstan. Ukrainians consider it an act of genocide. The Kremlin says food was intentionally withheld from peasants as a class, but not any ethnic group, and therefore cannot be considered a violation of the United Nations Genocide Convention, which does not mention class.

Another point of contention is Ukraine's World War II guerillas, who fought Soviets and Nazis after mistakenly welcoming Germans as liberators. They are seen as freedom fighters by Ukrainian President Viktor Yushchenko and as fascist collaborators by his Russian counterpart, Dmitri Medvedev.

Last month, Mr. Medvedev announced creation of a government commission to help prevent what he said was falsification of history that harms the interests of Russia. Mr. Medvedev says Russians are increasingly being confronted with what is known as historic falsification, and perhaps many have noticed that these attempts are becoming increasingly harsh, mean, and aggressive.

In Ukraine, President Viktor Yushchenko condemned foreign and domestic attempts to brand Ivan Mazepa as a traitor. Mr. Yushchenko says enough to looking at history through foreign eyes. He calls on Ukrainians to look at Mazepa with their own eyes, with Ukrainian eyes.

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Source:

http://www.voanews.com/english/2009-06-25-voa33.cfm

Tags:

Viktor Yushchenko, Dmitri Medvedev, Russian history, Ukrainian history, Ivan Mazepa, Serhiy poltavets, Soviet Union, Nazi Germany, Genocide, World War II, United Nations Genocide Convention, Kyiv, Moscow, Kremlin, Global Development News,

Posted via email from Global Business News

Tuition Soars in India

Once a fortnight, Bharati Prayag, a driver in New Delhi, used to treat himself to a chicken curry and a quarter bottle of rum. Earning a salary of 7,000 rupees ($144) a month and living in a hovel far from his wife and three children back in Shivan, a village in the state of Bihar, the curry and rum served to lift his spirits momentarily. But a year ago, his wife complained that the village school teacher was frequently absent leaving the pupils with no proper instruction.

Knowing his children would have no future without an education, 45-year-old Prayag, now sends home 800 rupees ($16) every month to pay for private tuition in maths and English for two of his children. "I don't mind forgoing my little treat. Their future is more important," he said. Like millions of poor Indians, Prayag has to send his children to a state school because it is free. But he knows the education they are getting there is mediocre and must be supplemented by a private tutor. Some Indians, both in villages and in urban slums, are so dismayed at teacher absenteeism in state schools that they make huge sacrifices to enrol their children in private schools.

A study conducted by Pratham, a non-governmental organisation providing education to under-privileged children, found that 65 per cent of slum schoolchildren in Hyderabad, south India, were registered at private schools. Mohammed Ansari, a farmer in Haryana, near New Delhi, says the teacher at his son's school is sometimes absent for weeks on end. "My son started school at [the age of] six. After three years, he still couldn't write a sentence or do simple addition," said Ansari.

Education system criticised

The malaise runs deep and wide; while the poor are unhappy with state schools and hire tutors for a basic education, the middle class is unsatisfied with the education provided at the top private schools. The middle class hires private tutors to compensate for declining teaching standards in private schools so that their children perform well in exams and secure a place at a good university.

"The mismatch between demand and supply is crazy. The shortage means that students have to score 95 per cent or more in their exams to get admission in the university of their choice," said New Delhi parent Anisa Tiwari. Tiwari's son, Nishant, 20, secured a place last year at St Stephen's College - an elite institution in New Delhi - largely because he scored 97 per cent in his final maths exam. "In India, if you don't get into a top university, you're wasting your time. So you have to make that superhuman effort to score top marks," Nishant said. Despite being exceptionally bright, he had tutors throughout secondary school to help him with maths, physics and chemistry.

A recent survey by the Associated Chambers of Commerce and Industry of India (Assocham) shows that middle class families spend one-third of their income every month on private tuition. The survey revealed that the use of private tutors has increased by between 40 and 45 per cent in the last few years.

Maths and sciences

Assocham's interviews with 5,000 students and parents across 11 cities in India indicated that maths, physics and chemistry were the main subjects for which tutors were needed. "Many schools conveniently push the ball back to parents, to tell them to engage private tutors for their kids. This is a serious failure in the education system," says D S Rawat, Assocham's secretary-general.

The result is a parallel education system in India. More than 80 per cent of tutors in the survey said that parents hired them to compensate for the deficiencies of school education. But Anuradha Awasti, a former maths teacher at Springdales School in New Delhi, says that tutoring weakens the students' independence and self-direct learning capabilities. She believes private tutorship hinders a child's reasoning and analytical abilities, and places too much emphasis on exams as opposed to genuine learning.

"With a tutor around, children are being spoon-fed instead of learning themselves and relying on their own resources and figuring things out for themselves. Tutors are a crutch," Awasti told Al Jazeera. Mohini Verma, an English teacher at Step-by-Step School just outside Delhi, says a child's extra-curricular activities should include time to play, daydream and relax."It saddens me that they have no space to breathe with all that pressure from so early on," she said.

Tuition traffic

Just as Prayag's sons trudge 3km to their tutor's house in another village, Akash Gupta, 12, is picked up each evening by the family driver and taken across New Delhi in rush hour traffic to his maths teacher's home in Saket. He changes out of his uniform in the car and has a snack on the way. "It's one of the best private schools in Delhi but the teaching is pathetic. His teachers give him homework on subjects they haven't covered properly in class so he can't do it alone," says Akash's mother Neha, a graphic designer.

"I'm a working mother with little time, so I had to get a tutor." Throughout urban India, on weekday evenings, a frenzied two-way traffic takes place. Tutors on their humble scooters rush across town to the homes of affluent children. If they cannot go to the children, the children are ferried to their homes or to coaching centres. Centres with names such as The Cambridge School in New Delhi and The Harvard Centre in Faridabad, just outside the capital, have sprung up all over India. Every evening, hundreds of children troop through the gates of these plush new buildings with air-conditioned rooms and manicured lawns.

Education has always been highly prized by Indians, not so much for its intrinsic worth but as the key to a better life. However, just 20 years ago, engaging a tutor for your child was an abnormality. Now, not having a tutor is a sign of parental dereliction. "You have the brightest students getting tutors to score good grades. It's become a ubiquitous crutch. Parents feel secure and the children also feel they have a safety net under them," child psychiatrist Megna Kapoor tells me.

Race to university

July is a stressful month for students who have applied to university. Jawaharlal Nehru University in the capital, for example, receives around 100,000 applications but accepts only 1,500. At the hugely respected Indian Institute of Management, 70,000 students fight every year for 200 places. At St Stephen's College 12,000 applicants compete for 450 places.

Despite the fact that half of India's population is below the age of 25, the Indian government has not built a new university for 50 years. India has 338 government universities. A government commission looking into the state of higher education said last month that it needed 1,500 universities. Kapil Sibal, India's education minister, has promised long overdue root-and-branch reform of the educational system, saying it had to be 'de-traumatised' for the sake of pupils and parents. He also plans to encourage foreign universities to open shop in India to alleviate the shortage of places. He also wants the Grade 10 exam for 15-year-olds to emphasise grading a pupil's work throughout the year so that the focus switches from marks-based to knowledge-based learning.

Blaming absenteeism, laziness

But critics of the private tutor culture say lazy teachers and mediocre teaching - even in some of the country's top private schools - is to blame. In state-owned rural schools, absentee teachers are virtually the norm. In Bihar, where Prayag comes from, 40 per cent of all schoolteachers are absent at any given time.

Instead of being in the classroom, they give private tuition to bump up their government salaries. Experts always point out that enrolling poor Indian children in school is easy. Their parents prize education above all else. It is keeping them in school that is difficult because of what they say is mind-numbingly boring teaching. "After a year or two, they drop out because it doesn't seem worthwhile. If they aren't going to school, then their parents send them out to earn to supplement the family income," says Mohini Kapoor, an education consultant.

When Prayag's sons talked about dropping out of school in Shivan a few years ago, he would have none of it and threatened to beat them. "This is about their future," he said. "Without maths and English they will never escape poverty."

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Source:

http://english.aljazeera.net/focus/2009/07/2009797207338966.html

Tags:

Chambers of Commerce and Industry of India Assocham, Global Best Practice, India has 338 government universities, Springdales School in New Delhi, Indian Education system, India Education, Indian Teachers, Kapil Sibal, India's education minister,

Posted via email from Global Business News

Haruki Murakami: Always on the Side of the Egg

I have come to Jerusalem today as a novelist, which is to say as a professional spinner of lies.

Of course, novelists are not the only ones who tell lies. Politicians do it, too, as we all know. Diplomats and military men tell their own kinds of lies on occasion, as do used car salesmen, butchers and builders. The lies of novelists differ from others, however, in that no one criticizes the novelist as immoral for telling them. Indeed, the bigger and better his lies and the more ingeniously he creates them, the more he is likely to be praised by the public and the critics. Why should that be?

My answer would be this: Namely, that by telling skillful lies - which is to say, by making up fictions that appear to be true - the novelist can bring a truth out to a new location and shine a new light on it. In most cases, it is virtually impossible to grasp a truth in its original form and depict it accurately. This is why we try to grab its tail by luring the truth from its hiding place, transferring it to a fictional location, and replacing it with a fictional form. In order to accomplish this, however, we first have to clarify where the truth lies within us. This is an important qualification for making up good lies.

Today, however, I have no intention of lying. I will try to be as honest as I can. There are a few days in the year when I do not engage in telling lies, and today happens to be one of them.

So let me tell you the truth. A fair number of people advised me not to come here to accept the Jerusalem Prize. Some even warned me they would instigate a boycott of my books if I came.

The reason for this, of course, was the fierce battle that was raging in Gaza. The UN reported that more than a thousand people had lost their lives in the blockaded Gaza City, many of them unarmed citizens - children and old people.

Any number of times after receiving notice of the award, I asked myself whether traveling to Israel at a time like this and accepting a literary prize was the proper thing to do, whether this would create the impression that I supported one side in the conflict, that I endorsed the policies of a nation that chose to unleash its overwhelming military power. This is an impression, of course, that I would not wish to give. I do not approve of any war, and I do not support any nation. Neither, of course, do I wish to see my books subjected to a boycott.

Finally, however, after careful consideration, I made up my mind to come here. One reason for my decision was that all too many people advised me not to do it. Perhaps, like many other novelists, I tend to do the exact opposite of what I am told. If people are telling me - and especially if they are warning me - "don't go there," "don't do that," I tend to want to "go there" and "do that." It's in my nature, you might say, as a novelist. Novelists are a special breed. They cannot genuinely trust anything they have not seen with their own eyes or touched with their own hands.

And that is why I am here. I chose to come here rather than stay away. I chose to see for myself rather than not to see. I chose to speak to you rather than to say nothing. This is not to say that I am here to deliver a political message. To make judgments about right and wrong is one of the novelist's most important duties, of course.

It is left to each writer, however, to decide upon the form in which he or she will convey those judgments to others. I myself prefer to transform them into stories - stories that tend toward the surreal. Which is why I do not intend to stand before you today delivering a direct political message.

Please do, however, allow me to deliver one very personal message. It is something that I always keep in mind while I am writing fiction. I have never gone so far as to write it on a piece of paper and paste it to the wall: Rather, it is carved into the wall of my mind, and it goes something like this:

"Between a high, solid wall and an egg that breaks against it, I will always stand on the side of the egg."

Yes, no matter how right the wall may be and how wrong the egg, I will stand with the egg. Someone else will have to decide what is right and what is wrong; perhaps time or history will decide. If there were a novelist who, for whatever reason, wrote works standing with the wall, of what value would such works be?

What is the meaning of this metaphor? In some cases, it is all too simple and clear. Bombers and tanks and rockets and white phosphorus shells are that high, solid wall. The eggs are the unarmed civilians who are crushed and burned and shot by them. This is one meaning of the metaphor.

This is not all, though. It carries a deeper meaning. Think of it this way. Each of us is, more or less, an egg. Each of us is a unique, irreplaceable soul enclosed in a fragile shell. This is true of me, and it is true of each of you. And each of us, to a greater or lesser degree, is confronting a high, solid wall. The wall has a name: It is The System. The System is supposed to protect us, but sometimes it takes on a life of its own, and then it begins to kill us and cause us to kill others - coldly, efficiently, systematically.

I have only one reason to write novels, and that is to bring the dignity of the individual soul to the surface and shine a light upon it. The purpose of a story is to sound an alarm, to keep a light trained on The System in order to prevent it from tangling our souls in its web and demeaning them. I fully believe it is the novelist's job to keep trying to clarify the uniqueness of each individual soul by writing stories - stories of life and death, stories of love, stories that make people cry and quake with fear and shake with laughter. This is why we go on, day after day, concocting fictions with utter seriousness.

My father died last year at the age of 90. He was a retired teacher and a part-time Buddhist priest. When he was in graduate school, he was drafted into the army and sent to fight in China. As a child born after the war, I used to see him every morning before breakfast offering up long, deeply-felt prayers at the Buddhist altar in our house. One time I asked him why he did this, and he told me he was praying for the people who had died in the war.

He was praying for all the people who died, he said, both ally and enemy alike. Staring at his back as he knelt at the altar, I seemed to feel the shadow of death hovering around him.

My father died, and with him he took his memories, memories that I can never know. But the presence of death that lurked about him remains in my own memory. It is one of the few things I carry on from him, and one of the most important.

I have only one thing I hope to convey to you today. We are all human beings, individuals transcending nationality and race and religion, fragile eggs faced with a solid wall called The System. To all appearances, we have no hope of winning. The wall is too high, too strong - and too cold. If we have any hope of victory at all, it will have to come from our believing in the utter uniqueness and irreplaceability of our own and others' souls and from the warmth we gain by joining souls together.

Take a moment to think about this. Each of us possesses a tangible, living soul. The System has no such thing. We must not allow The System to exploit us. We must not allow The System to take on a life of its own. The System did not make us: We made The System.

That is all I have to say to you.

I am grateful to have been awarded the Jerusalem Prize. I am grateful that my books are being read by people in many parts of the world. And I am glad to have had the opportunity to speak to you here today.

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Source:

http://www.haaretz.com/hasen/spages/1064909.html

Tags:

Haruki Murakami, Haaretz, The Jerusalem Prize, Palestine, Gaza, Literary prize, Literature, Japan, Japanese authors, acceptance speech, acceptance lecture, UN, Global Best Practice, China,

Posted via email from Global Business News

Disorderly Genius: How Chaos Drives The Brain

HAVE you ever experienced that eerie feeling of a thought popping into your head as if from nowhere, with no clue as to why you had that particular idea at that particular time? You may think that such fleeting thoughts, however random they seem, must be the product of predictable and rational processes. After all, the brain cannot be random, can it? Surely it processes information using ordered, logical operations, like a powerful computer?

Actually, no. In reality, your brain operates on the edge of chaos. Though much of the time it runs in an orderly and stable way, every now and again it suddenly and unpredictably lurches into a blizzard of noise.

Neuroscientists have long suspected as much. Only recently, however, have they come up with proof that brains work this way. Now they are trying to work out why. Some believe that near-chaotic states may be crucial to memory, and could explain why some people are smarter than others.

In technical terms, systems on the edge of chaos are said to be in a state of "self-organised criticality". These systems are right on the boundary between stable, orderly behaviour - such as a swinging pendulum - and the unpredictable world of chaos, as exemplified by turbulence.

The quintessential example of self-organised criticality is a growing sand pile. As grains build up, the pile grows in a predictable way until, suddenly and without warning, it hits a critical point and collapses. These "sand avalanches" occur spontaneously and are almost impossible to predict, so the system is said to be both critical and self-organising. Earthquakes, avalanches and wildfires are also thought to behave like this, with periods of stability followed by catastrophic periods of instability that rearrange the system into a new, temporarily stable state.

Self-organised criticality has another defining feature: even though individual sand avalanches are impossible to predict, their overall distribution is regular. The avalanches are "scale invariant", which means that avalanches of all possible sizes occur. They also follow a "power law" distribution, which means bigger avalanches happen less often than smaller avalanches, according to a strict mathematical ratio. Earthquakes offer the best real-world example. Quakes of magnitude 5.0 on the Richter scale happen 10 times as often as quakes of magnitude 6.0, and 100 times as often as quakes of magnitude 7.0.

These are purely physical systems, but the brain has much in common with them. Networks of brain cells alternate between periods of calm and periods of instability - "avalanches" of electrical activity that cascade through the neurons. Like real avalanches, exactly how these cascades occur and the resulting state of the brain are unpredictable.

It might seem precarious to have a brain that plunges randomly into periods of instability, but the disorder is actually essential to the brain's ability to transmit information and solve problems. "Lying at the critical point allows the brain to rapidly adapt to new circumstances," says Andreas Meyer-Lindenberg from the Central Institute of Mental Health in Mannheim, Germany.

Disorder is essential to the brain's ability to transmit information and solve problems

The idea that the brain might be fundamentally disordered in some way first emerged in the late 1980s, when physicists working on chaos theory - then a relatively new branch of science - suggested it might help explain how the brain works.

The focus at that time was something called deterministic chaos, in which a small perturbation can lead to a huge change in the system - the famous "butterfly effect". That would make the brain unpredictable but not actually random, because the butterfly effect is a phenomenon of physical laws that do not depend on chance. Researchers built elaborate computational models to test the idea, but unfortunately they did not behave like real brains. "Although the results were beautiful and elegant, models based on deterministic chaos just didn't seem applicable when looking at the human brain," says Karl Friston, a neuroscientist at University College London. In the 1990s, it emerged that the brain generates random noise, and hence cannot be described by deterministic chaos. When neuroscientists incorporated this randomness into their models, they found that it created systems on the border between order and disorder - self-organised criticality.

More recently, experiments have confirmed that these models accurately describe what real brain tissue does. They build on the observation that when a single neuron fires, it can trigger its neighbours to fire too, causing a cascade or avalanche of activity that can propagate across small networks of brain cells. This results in alternating periods of quiescence and activity - remarkably like the build-up and collapse of a sand pile.

Neural avalanches

In 2003, John Beggs of Indiana University in Bloomington began investigating spontaneous electrical activity in thin slices of rat brain tissue. He found that these neural avalanches are scale invariant and that their size obeys a power law. Importantly, the ratio of large to small avalanches fit the predictions of the computational models that had first suggested that the brain might be in a state of self-organised criticality (The Journal of Neuroscience, vol 23, p 11167).

To investigate further, Beggs's team measured how many other neurons a single cell in a slice of rat brain activates, on average, when it fires. They followed this line of enquiry because another property of self-organised criticality is that each event, on average, triggers only one other. In forest fires, for example, each burning tree sets alight one other tree on average - that's why fires keep going, but also why whole forests don't catch fire all at once.

Sure enough, the team found that each neuron triggered on average only one other. A value much greater than one would lead to a chaotic system, because any small perturbations in the electrical activity would soon be amplified, as in the butterfly effect. "It would be the equivalent of an epileptic seizure," says Beggs. If the value was much lower than one, on the other hand, the avalanche would soon die out.

Beggs's work provides good evidence that self-organised criticality is important on the level of small networks of neurons. But what about on a larger scale? More recently, it has become clear that brain activity also shows signs of self-organised criticality on a larger scale.

As it processes information, the brain often synchronises large groups of neurons to fire at the same frequency, a process called "phase-locking". Like broadcasting different radio stations at different frequencies, this allows different "task forces" of neurons to communicate among themselves without interference from others.

The brain also constantly reorganises its task forces, so the stable periods of phase-locking are interspersed with unstable periods in which the neurons fire out of sync in a blizzard of activity. This, again, is reminiscent of a sand pile. Could it be another example of self-organised criticality in the brain?

In 2006, Meyer-Lindenberg and his team made the first stab at answering that question. They used brain scans to map the connections between regions of the human brain and discovered that they form a "small-world network" - exactly the right architecture to support self-organised criticality.

Small-world networks lie somewhere between regular networks, where each node is connected to its nearest neighbours, and random networks, which have no regular structure but many long-distance connections between nodes at opposite sides of the network (see diagram). Small-world networks take the most useful aspects of both systems. In places, the nodes have many connections with their neighbours, but the network also contains random and often long links between nodes that are very far away from one another.

For the brain, it's the perfect compromise. One of the characteristics of small-world networks is that you can communicate to any other part of the network through just a few nodes - the "six degrees of separation" reputed to link any two people in the world. In the brain, the number is 13.

Meyer-Lindenberg created a computer simulation of a small-world network with 13 degrees of separation. Each node was represented by an electrical oscillator that approximated a neuron's activity. The results confirmed that the brain has just the right architecture for its activity to sit on the tipping point between order and disorder, although the team didn't measure neural activity itself (Proceedings of the National Academy of Sciences, vol 103, p 19518).

That clinching evidence arrived earlier this year, when Ed Bullmore of the University of Cambridge and his team used brain scanners to record neural activity in 19 human volunteers. They looked at the entire range of brainwave frequencies, from 0.05 hertz all the way up to 125 hertz, across 200 different regions of the brain.

Power laws again

The team found that the duration both of phase-locking and unstable resynchronisation periods followed a power-law distribution. Crucially, this was true at all frequencies, which means the phenomenon is scale invariant - the other key criterion for self-organised criticality.

What's more, when the team tried to reproduce the activity they saw in the volunteers' brains in computer models, they found that they could only do so if the models were in a state of self-organised criticality (PLoS Computational Biology, vol 5, p e1000314). "The models only showed similar patterns of synchronisation to the brain when they were in the critical state," says Bullmore.

The work of Bullmore's team is compelling evidence that self-organised criticality is an essential property of brain activity, says neuroscientist David Liley at Swinburne University of Technology in Melbourne, Australia, who has worked on computational models of chaos in the brain. But why should that be? Perhaps because self-organised criticality is the perfect starting point for many of the brain's functions.

The neuronal avalanches that Beggs investigated, for example, are perfect for transmitting information across the brain. If the brain was in a more stable state, these avalanches would die out before the message had been transmitted. If it was chaotic, each avalanche could swamp the brain.

At the critical point, however, you get maximum transmission with minimum risk of descending into chaos. "One of the advantages of self-organised criticality is that the avalanches can propagate over many links," says Beggs. "You can have very long chains that won't blow up on you."

Self-organised criticality also appears to allow the brain to adapt to new situations, by quickly rearranging which neurons are synchronised to a particular frequency. "The closer we get to the boundary of instability, the more quickly a particular stimulus will send the brain into a new state," says Liley.

It may also play a role in memory. Beggs's team noticed that certain chains of neurons would fire repeatedly in avalanches, sometimes over several hours (The Journal of Neuroscience, vol 24, p 5216). Because an entire chain can be triggered by the firing of one neuron, these chains could be the stuff of memory, argues Beggs: memories may come to mind unexpectedly because a neuron fires randomly or could be triggered unpredictably by a neuronal avalanche.

The balance between phase-locking and instability within the brain has also been linked to intelligence - at least, to IQ. Last year, Robert Thatcher from the University of South Florida in Tampa made EEG measurements of 17 children, aged between 5 and 17 years, who also performed an IQ test.

The balance between stability and instability in the brain has been linked with intelligence, at least as measured by scores on an IQ test

He found that the length of time the children's brains spent in both the stable phase-locked states and the unstable phase-shifting states correlated with their IQ scores. For example, phase shifts typically last 55 milliseconds, but an additional 1 millisecond seemed to add as many as 20 points to the child's IQ. A shorter time in the stable phase-locked state also corresponded with greater intelligence - with a difference of 1 millisecond adding 4.6 IQ points to a child's score (NeuroImage, vol 42, p 1639).

Thatcher says this is because a longer phase shift allows the brain to recruit many more neurons for the problem at hand. "It's like casting a net and capturing as many neurons as possible at any one time," he says. The result is a greater overall processing power that contributes to higher intelligence.

Hovering on the edge of chaos provides brains with their amazing capacity to process information and rapidly adapt to our ever-changing environment, but what happens if we stray either side of the boundary? The most obvious assumption would be that all of us are a short step away from mental illness. Meyer-Lindenberg suggests that schizophrenia may be caused by parts of the brain straying away from the critical point. However, for now that is purely speculative.

Thatcher, meanwhile, has found that certain regions in the brains of people with autism spend less time than average in the unstable, phase-shifting states. These abnormalities reduce the capacity to process information and, suggestively, are found only in the regions associated with social behaviour. "These regions have shifted from chaos to more stable activity," he says. The work might also help us understand epilepsy better: in an epileptic fit, the brain has a tendency to suddenly fire synchronously, and deviation from the critical point could explain this.

"They say it's a fine line between genius and madness," says Liley. "Maybe we're finally beginning to understand the wisdom of this statement."

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Tags:

phase-shifting, social behaviour, IQ, EEG measurements, Meyer-Lindenberg, Power laws, self-organised criticality, "power law" distribution, epilepsy, "phase-locking", Global Development News,

Source:

http://www.newscientist.com/article/mg20227141.200-disorderly-genius-how-chaos-drives-the-brain.html?full=true

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